The Buda Health Center is one of the leading private institutions of Budapest offering its patients personalized comprehensive health care.

Magyar

Major, Zoltán, Zsigmond, MD

Professional experience

  • MEDFUTURE Research Center, Iuliu Hațieganu University of Medicine and Pharmacy
    • Research doctor
  • Department of Neurology, Clinic of Cluj-Napoca
    • Head of Department
  • National Center for Spinal Disorders
  • 2018 – : Buda Health Center

Education and qualifications

  • 2004: Faculty of Medicine – Iuliu Hațieganu University of Medicine and Pharmacy
  • 2005: Clinical Pharmacology MSc, Iuliu Hațieganu University of Medicine and Pharmacy
  • 2010: Ph.D., Iuliu Hațieganu University of Medicine and Pharmacy
  • 2012: qualifying exam in neurology
  • 2015: Postdoctoral Course, Iuliu Hațieganu University of Medicine and Pharmacy
  • Electroencephalography
  • Electromyography

Language skills

  • English
  • German
  • Romanian

Professional and society membership

  • Hungarian Clinical Neurophysiology Society
  • Hungarian Epilepsy League

Scientific activity

  • Number of articles: 4
  • Number of book chapters: 1
  • Number of specialist presentations: 18
  • Number of scientific projects: 8
  • Foreign or courses in Romania by foreign institutions
    • 22.04.-23.04.2008. - Meet the professor - Intensive epileptology training – workshop Zentrum Epilepsie Erlangen (ZEE), Erlangen, Germany

    • 19.07. – 27.07.2008. - 7th Summer School of Myology – Institut de Miologie Hospital Pitie-Salpetriere, Paris, France

    • 31.05.-04.06.2010. – PRIME Course Teaching and Learning, a course for medical educators – University of Brighton, Cluj-Napoca, Romania

    • 16.09.2010. – The multidisciplinary approach to NMDs: towards a harmonised practice – TREAT-NMD training, Milan, Italy

    • 28.06. – 29.06.2011. – LabAuthor Software training: LabAuthor Level I – Editing LabTutor Experiments, LabAuthor Level II – Creating New LabTutor Experiments – Oxford, UK

    • 02.09.-06.11.2014. – Writing in the Sciences – Stanford University - on-line course

    • 23.02.-27.02.2015. – Intraoperative neurophysiological monitoring training - National Center for Spinal Disorders, Budapest, Hungary

    • 12.11.-13.11.2015. – Intraoperative neurophysiological monitoring training - National Center for Spinal Disorders, Budapest, Hungary

    • 08.02.-12.02.2016 – Long-term epilepsy monitoring and intraoperative neurophysiological monitoring (ECoG) - National Institute for Clinical Neurosciences, Budapest, Hungary

    • 28.11.-06.12.2016 – Long-term EEG monitoring, including invasive EEG methods and ECoG – strip electrodes, sEEG, and intraoperative monitoring – National Institute for Clinical Neurosciences, Budapest, Hungary

    • 07.12.-09.12.2016 – Intraoperative neurophysiological monitoring training – National Center for Spinal Disorders, Budapest, Hungary

    • 22.02.-24.02.2017 – NIM Eclipse Neurophys Training – Neuromonitoring in Spine, Cranial & Cardiovascular Surgeries – Tolochenaz, Switzerland

    • 27.03.-31.03.2017 – Long-term EEG monitoring, including invasive EEG methods and ECoG – strip electrodes, sEEG, and intraoperative monitoring – National Institute for Clinical Neurosciences, Budapest, Hungary

    • 28.09.2017. – International workshop on New Trends in Rehabilitation Robotics, Cluj-Napoca, Romania

    • 27.11.-01.12.2017. – Intraoperative monitoring and epilepsy monitoring – observational training – Hopitaux Universitaires Geneve, Geneva, Switzerland

    • 08.12.2017. – Exchange programme: Introduction to LCIG therapy – Neurology Department, Semmelweis University, Budapest, Hungary
  • Courses at domestic (Romanian) institutions’ 
    • 13.03.-17.03.2006 – Electroneurografie si electromiografie – UMF „Iuliu Hatieganu”, Cluj-Napoca, Romania

    • 19.09.2007. – Educational Course: Focal Epilepsies in Childhood – EUREPA – European Epilepsy Academy, Sinaia, Romania

    • 22.10.-27.10.2007. – EMG, EEG si polisomnografie - UMF „Iuliu Hatieganu”, Cluj-Napoca, Romania

    • 24.05.-25.04.2008 – Baze in EMG si Neurografie – UMF „Carol Davila”/Akademiska Sjukhuset (Uppsala), Bucuresti, Romania

    • 14.05.-16.05.2009 – Traditie si progres in Farmacologie, Toxicologie si Oncologie clinica. Farmacologie, Algeziologie. Algeziologie pentru studenti si tineri medici – UMF „Gr.T. Popa”, Iasi, Romania

    • 13.05.-15.05.2010. – Durerea la copil si adolescent. Farmacologie, Algeziologie. Algeziologie pentru studenti si tineri medici – UMF „Gr.T. Popa”, Iasi, Romania

    • 18.03.2011. – Standards of care in the management of people with DMD – TREAT-NMD training, Bucuresti, Romania

    • 30.03.2012. – Initiere si diagnostic electroencefalografic – UMF „Carol Davila”, Bucuresti, Romania (durata 3 saptamani)

    • 30.11.2012. – Initiere si diagnostic electromiografic si neurografic - UMF „Carol Davila”, Bucuresti, Romania (durata 2 saptamani)

    • 01.03.2013. – Diagnosticul electromiografic si electroneurografic al afectiunilor neurologice si neurochirurgicale - UMF „Carol Davila”, Bucuresti, Romania (durata 2 saptamani)

    • 18.04.-20.04.2013. – Managementul Calitaii in Sectorul Medical si Comunicare Institutionala – Colegiul Medicilor Satu-Mare/CREST – Baile 1 Mai, Romania

    • 19.02.2015. – Seminariile Departamentului de Neurostiinte – Cluj-Napoca, Romania

    • 01.06.-04.06.2015. – RoNeuro Brain Days – Cluj-Napoca, Romania

    • 26.05.-27.05.2017. – Management of advanced Parkinson’s Disease with Infusion Therapies course - Bucuresti, Romania

    • 22.05.2017. - Workshop: Current and future applications of non-invasive and invasive BCIs - Cluj-Napoca, Romania
  • Publications
    • Original full-text research articles published in Thomson-Reuters Web of Science (ISI) indexed journals:

      • Meszaros I, Krausz TL, Fischer FE, Major ZZ, Popescu O. “Expression of immunomodulatory genes in inflammatory and autoimmune diseases.” Romanian Biotechnological Letters. 2010;6:5729-37

      • Major ZZ. “Combined Evoked potentials in co-occuring ADHD and Epilepsy”. Ideggyogy Sz. 2011;64(7–8):248–56

      • Krausz LT, Fischer-Fodor E, Major ZZ, Fetica B. “GITR-expressing regulatory T-cell subsets are increased in tumor-positive lymph nodes from advanced breast cancer patients as compared to tumor-negative lymph nodes”. Int J Immunopathol Pharmacol. 2012;25(1):59-66.

      • Axente DD, Silaghi H, Silaghi CA, Major ZZ, Micu CM, Constantea NA.”Operative outcomes of robot-assisted transaxillary thyroid surgery for benign thyroid disease: early experience in 50 patients.” Langenbecks Arch Surg. 2013 Aug;398(6):887-94.

      • Axente DD, Major ZZ, Micu CM, Constantea NA. “Technical Particularities of the Robot-Assisted Trans-Axillary Thyroidectomy.” Chirurgia. 2013;108(3):422-28

      • Major ZZ, Văcăraş V, Buzoianu AD, Mureşanu FD. “Glatiramer Acetate Treatment-Related Effects on Visual EPs and P300 Wave in Patients Suffering from Multiple Sclerosis.” Neurophysiology. 2013;45(3):234-242.

      • Krausz LT, Major ZZ, Muresanu DF, Chelaru E, Nocentini G, Riccardi C. “Characterization of CD4+ and CD8+ Tregs in a Hodgkin’s lymphoma patient presenting with myasthenia-like symptoms.” Ideggyogy Sz 2013;66(9–10):343–348.

      • Văcăraş V, Major ZZ, Muresanu DF, Krausz LT, Marginean I, Buzoianu AD. “Effect of glatiramer acetate on peripheral blood BDNF and phosphorylated TrkB levels in relapsing-remitting multiple sclerosis”. CNS & Neurological Disorders – Drug Targets. 06/2014; 13(4):647-651. DOI: 10.2174/1871527313666140618110049

      • Văcăraș V, Major ZZ, Mariș E, Major KA, Buzoianu AD. [Multiple sclerosis with stroke-like symptoms: a diagnostic challenge. Case report]. Orv Hetil 2015;156(37):1514–1518.

      • Major ZZ, Vacaras V, Maris E, Crisan I, Florea B, Major KA, Muresanu DF. “The electrophysiological changes after 1Hz rTMS in ALS patients. A pilot study.” Ideggyogy Sz 2016;69(3–4):E026–E031.

      • Vacaras V, Vithoulkas G, Buzoianu AD, Marginean I, Major ZZ, Vacaras V, Nicoara RD, Oberbaum M. “Homeopathic Treatment for Postpartum Depression: A Case Report.” Journal of Evidence-Based Complementary & Alternative Medicine 2016;(2016):1-4

      • Vacaras V, Major ZZ, Buzoianu AD. “Brain-derived neurotrophic factor levels under chronic natalizumab treatment in multiple sclerosis. A preliminary report.” Neurol Neurochir Pol 2017, (51):221-226.

      • Axente DD, Major ZZ, Dudric VN, Constantea NA. “Control of the functionality of the brachial plexus during robot-assisted transaxillary thyroid surgery.” Neurophysiology 2017; 49(4): 295-300.

    • Meeting abstracts published in Thomson-Reuters Web of Science (ISI) indexed journals:

      • Buzoianu AD, Bocsan IC, Militaru FC, Major ZZ. “The effects of topiramate on acute anxiety models in rats.” Eur Neuropsychopharm. 2008;18(Suppl 4):S502-503

      • Bocsan IC, Buzoianu AD, Militaru FC, Major ZZ. “The influence of lamotrigine on rat behaviour. “Basic Clin Pharmacol. 2009;105:148

      • Buzoianu AD, Bocsan IC, Maier C, Trifa A, Militaru FC, Perju-Dumbrava L, Major ZZ. “Genotype–phenotype correlations between the CYPC19 polymorphism and pharmacokinetic parameters in Romanian epileptic patients.” Eur Neuropsychopharm. 2011;21(Suppl 3):S284

      • Bocsan IC, Buzoianu AD, Major ZZ, Maier C, Trifa AP, Popp RA, Militaru FC, Perju-Dumbrava L, Popescu C. “The MDR1 C3435T polymorphism and valproic acid plasmatic level in Romanian epileptic patients.” Eur Neuropsychopharm. 2011;21(Suppl 3):S287

    • Proceedings papers published in Thomson-Reuters Web of Science (ISI) indexed journals:

      • Bocsan IC, Buzoianu AD, Militaru FC, Major ZZ. The influence of lamotrigine on rat behaviour. Reprinted from 9th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT) International Proceedings. Medimond

    • Original full-text research articles published in journals indexed in international databases (non-ISI):

      • Şandor Vl, Volda M, Bocşan CI, Şandor CT, Meszaros I, Major ZZ, Krausz LT. “Comparative effects of keto-phenylbutazone and streptokinase on UV-induced skin inflammation in guinea pigs.” Timişoara Medical Journal 2006;56(2):280-283.

      • Major ZZ, Benga I. “Treatment options in ADHD.” Clujul Medical. 2009;82(4):484-487.

      • Major ZZ, “Benga I. Stimulus related potentials in ADHD-epilepsy comorbidity in children. Preliminary report.” Clujul Medical. 2010;83(2):313-317.

      • Bocsan C, Major ZZ, Maier C, Popp R, Iuga C, Trifa A, Militaru FC, Buzoianu AD. “Study of the phenotypic variation expression in the metabolizing status of Romanian epileptic patients.” Therapeutics Pharmacology and Clinical Toxicology. 2010;3:224-28.

      • Major ZZ, Buzoianu AD, Perju-Dumbrava L, Marginean I, Bocsan IC, Major KA. QEEG: “Relative power findings in epilepsy.” Therapeutics Pharmacology and Clinical Toxicology. 2010;4:269-73.

      • Major ZZ, Buzoianu AD, Perju-Dumbravă L, Mărginean I, Krausz LT, Văcăraş V et al. “The effect of epilepsy on the age-related prolongation of the P300.” Fiziologia/Physiology. 2010;20(4):24-7.

      • Buzoianu AD, Bocşan IC, Maier C, Trifa AP, Popp RA, Perju Dumbrava L, Sabin O, Militaru C, Brusturean E, Major ZZ, Popescu O. “Genotype-phenotype correlations between the alleles of the MDR1 C3435T polymorphism and pharmacokinetic parameters in Romanian epileptic patients.” Therapeutics Pharmacology and Clinical Toxicology. 2011;1:40-44.

      • Vacaras V, Major ZZ, Buzoianu AD. “Disease modifying pharmacological approach of multiple sclerosis. A focus on Glatiramer acetate.” Therapeutics Pharmacology and Clinical Toxicology. 2011;15(4):265-69.

      • Văcăraş V, Major ZZ, Buzoianu AD. “One year on glatiramer acetate. Preliminary report on disease activity and disability evolution.” HVM Bioflux. 2012;4(3):107-109.

      • Văcăraş V, Major ZZ, Seewooram R, Major KA, Muresanu DF, Buzoianu AD. “Disease activity and disability evolution under glatiramer acetate: A clinical approach.” Neuropsychopharmacol Hung. 2014 Mar;16(1):11-8.

      • Văcăraș V, Major ZZ, Mariș E, Major KA, Buzoianu AD. “A stepwise approach to adult onset leukodystrophy.” HVM Bioflux 2015;7(3):191-196.

      • Major ZZ, Văcăraș V, Major KA, Mariș E, Mureșanu DF. “Wilson’s disease – a six year long journey to a positive diagnosis.” HVM Bioflux 2015;7(3):225-228.

      • Major KA, Major ZZ, Carbone G, Pîslă A, Vaida C, Gherman B, Pîslă DL. “Ranges of motion as basis for robot-assisted post-stroke rehabilitation.” HVM Bioflux 2016;8(4):192-196.

      • Vaida C, Carbone G, Major KA, Major ZZ, Plitea N, Pisla D. “On human robot interaction modalities in the upper limb rehabilitation after stroke.” Acta Technica Napocensis Series: Applied mathematics, Mechanics and Engineering, 2017;60(1):91-102.

      • Major KA, Carbone G, Major ZZ, Vaida C, Pisla D. “Predefined assessment tools in robot assisted physical therapy after stroke.” Bulletin of theTransilvania University of Braşov, 2017;10(59)1:1-6.

    • Meeting abstracts published in journals indexed in international databases (non-ISI):

      • Tomescu-Baciu A, Krausz LT, Major ZZ. “Immune receptor and cytokine expression in PMBC of Multiple Sclerosis patients.” Romanian Journal of Biochemistry. 2009;46(Supplementa):69.

      • Banias-Palaghita L, Major ZZ, Catana C, Krausz TL, Vl Sandor. “Terapia cu fumaraţi în scleroza multiplă.” Medicina moderna. 2009;16(Suppl1):65-67.

      • Şandor Vl, Danciu MM, Major ZZ, Gheban D, Sabin O, Butură A, Trîmbiţaş S. “Histo-chemical changes produced by reserpine and dopamine in the adrenal medulla.” Therapeutics Pharmacology and Clinical Toxicology. 2010;14(Supplement 3):37.

      • Şandor Vl, Niculae CE, Pătrulescu AM, Magyar DS, Major ZZ. “The effects of fenoldopam in immobilization-induced gastric ulcers.” Therapeutics Pharmacology and clinical Toxicology. 2010;14(Supplement 3):39.

      • Major ZZ, Alda G. “Neuromyelitis optica. Case report.” Clujul Medical 2013;86(Supplement 3):S207

    • Proceedings papers published in national journals (non-ISI):

      • Sandor Vl, Amza LC, Kenez EA, Major ZZ, Magyar DS, Chirica M et al. Efectul amfetaminei in administrare acuta in convulsiile prin pentetrazol. Pain and Drug Research – Zilele Medicamentului Editia a XIX-a. 2010;(Proceeding):29-34. ISSN: 1843-1038

      • Sandor Vl, Scurtea DM, Andresan-Marele FC, Gosa D, Butura A, Major ZZ, Kenez EA. Influenta tolperisonei asupra efectelor stricninei la broasca si soarece. Pain and Drug Research – Zilele Medicamentului Editia a XIX-a. 2010;(Proceeding):35-40. ISSN: 1843-1038

    • Book chapters

      • Buzoianu AD, Militaru CF, Bocşan CI, Zoltan MZ. “Antidepressants in the treatment of pain.” In: Neurosciences: clinical application of recent knowledge (Eds. Dumitraşcu DL, Hoţoleanu C). Ed. Medicală Universitară “Iuliu Haţieganu”, Cluj-Napoca. 2008; 148-157. ISBN 978-973-693-289-2


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Patient safety protocol

We consider the safety of our patients and our professionals to be of the utmost importance, therefore, in accordance with the current regulations in force, we implement several protective measures against COVID-19 in our Institute, which you can read about in detail HERE. A negative PCR test is required for oral and other body cavity examinations or interventions if the patient had a positive PCR test in the last 3 weeks prior to the test.

The high level of interest in coronavirus testing has proportionally increased the workload of our telephone customer service. In order to improve our service, we provide a dedicated telephone line for corona virus test appointments: +36 1 999-1727
At the above telephone number - on weekdays between 8 a.m. and 8 p.m. - our colleagues only book appointments for coronavirus testing.

To download the on-site pre-screening questionnaire, please click HERE!

In order to provide mandatory information to the National eHealth Infrastructure (EESZT) in accordance with legal regulations, the basic condition for starting care for all Hungarian citizens is to provide the number of the social security identification card ("TAJ kártya") and to provide credible proof of your personal data. In the case of foreign nationals who do not have a TAJ, the number of the foreign travel document will be recorded.